منابع مشابه
Diagnostic metagenomics: potential applications to bacterial, viral and parasitic infections
The term 'shotgun metagenomics' is applied to the direct sequencing of DNA extracted from a sample without culture or target-specific amplification or capture. In diagnostic metagenomics, this approach is applied to clinical samples in the hope of detecting and characterizing pathogens. Here, I provide a conceptual overview, before reviewing several recent promising proof-of-principle applicati...
متن کاملViral Metagenomics: Analysis of Begomoviruses by Illumina High-Throughput Sequencing
Traditional DNA sequencing methods are inefficient, lack the ability to discern the least abundant viral sequences, and ineffective for determining the extent of variability in viral populations. Here, populations of single-stranded DNA plant begomoviral genomes and their associated beta- and alpha-satellite molecules (virus-satellite complexes) (genus, Begomovirus; family, Geminiviridae) were ...
متن کاملComparative Viral Metagenomics of Environmental Samples from Korea
The introduction of metagenomics into the field of virology has facilitated the exploration of viral communities in various natural habitats. Understanding the viral ecology of a variety of sample types throughout the biosphere is important per se, but it also has potential applications in clinical and diagnostic virology. However, the procedures used by viral metagenomics may produce technical...
متن کاملBroad Surveys of DNA Viral Diversity Obtained through Viral Metagenomics of Mosquitoes
Viruses are the most abundant and diverse genetic entities on Earth; however, broad surveys of viral diversity are hindered by the lack of a universal assay for viruses and the inability to sample a sufficient number of individual hosts. This study utilized vector-enabled metagenomics (VEM) to provide a snapshot of the diversity of DNA viruses present in three mosquito samples from San Diego, C...
متن کاملMetagenomics
EditoriAL EditoriAL Estimates suggest that less than 1% of the microorganisms present in most habitats on Earth are culturable, 1 which means that our current view of the structural and functional diversity of the microbial world is severely limited and its vast emporium of potential medicines and useful industrial products lies virtually untapped. Furthermore, our historical reliance on cultur...
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ژورنال
عنوان ژورنال: Reviews in Medical Virology
سال: 2007
ISSN: 1052-9276,1099-1654
DOI: 10.1002/rmv.532